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DOSAGE FORM: Lyophilized Injection, 200mg/vial, 400mg/vial


Teicoplanin is an antibiotic glycopeptide. Its antibiotic action involves the inhibition of peptidoglycan synthesis in the cell wall of gram-positive bacteria. The molecule is comprised of 5 major components joined by specific fatty acid moieties. Teicoplanin has 20 chiral centers and 4 fused rings and, like vancomycin has a complex structure that provides a wide range of polar, dispersive and potential ionic interactive sites.


Inflammation of the lining of the heart cavity and heart valves due to infection (endocarditis)

Prevention of infection (usually after surgery).

Severe infections.

Treatment of serious staphylococcal bacterial infections.

Used in moderate to severe infections with Gram-positive organisms.

Teicoplanin is extremely useful in the following clinical situations:

Severe lower respiratory tract infections with presumed or documented Gram- positive infection.

Infection where "methicillin-resistant Staphylococcus aureus" (MRSA) is documented or suspected.


Teicoplanin belongs to a group of antibiotics called glycopeptides. Bacteria have an external cell wall that is reinforced by molecules called peptidoglycans. The cell wall is vital for protection against the normal environment of the body in which the bacteria live. Teicoplnin works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and this result in the death of the bacteria. Teicoplanin is used to treat serious infections of the heart and blood. It is not absorbed from the gut and is therefore only given by injection or infusion.


Assay NLT 90% - NMT 110%  of labelled aprotinin.
Identification Compies to BP
PH 5.0 – 7.0
High molecular weight proteins Complies  BP
BET NMT 0.778 EU per 5.56 Ph.Eur of aprotinin